| U. S. Senator -- Democratic Party All 3877 precincts reporting Click here for Results by Parish | |||
| Neeson J. Chauvin, Jr. (D) | 17.72% | 19521 | |
| Cary J. Deaton (D) | 11.67% | 12853 | |
| "Charlie" Melancon (D) | 70.62% | 77809 | |
| U. S. Senator -- Libertarian Party All 3877 precincts reporting Click here for Results by Parish | |||
| Anthony Gentile (L) | 38.38% | 953 | |
| Randall Todd Hayes (L) | 61.62% | 1530 | |
| U. S. Senator -- Republican Party All 3877 precincts reporting Click here for Results by Parish | |||
| Nick J. Accardo (R) | 5.38% | 5232 | |
| Chet D. Traylor (R) | 7.03% | 6841 | |
| David Vitter (R) | 87.59% | 85225 | |